Mechanisms Perforin-Dependent CTL Effector Virally Infected Hepatocytes Are Resistant to
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چکیده
منابع مشابه
Virally infected hepatocytes are resistant to perforin-dependent CTL effector mechanisms.
Cell-mediated cytotoxicity plays an important role in the clearance of noncytopathic viruses from infected tissues. Perforin-dependent cytotoxic mechanisms have been noted to play an important role in the clearance of infections from multiple extrahepatic organs. In contrast, mice with defects in the Fas/Fas ligand (FasL)-mediated cytotoxicity pathway exhibit delayed clearance of adenovirus fro...
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تاریخ انتشار 2001